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HAMA M520 Optical Mouse Driver

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HAMA M520 Optical Mouse Driver

Abstract Optical coherence tomography OCT is a promising research tool for brain imaging and developmental biology.

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Serving as a three-dimensional optical biopsy technique, OCT provides HAMA M520 Optical Mouse reconstruction of brain tissues and embryonic structures with micrometer resolution and video rate imaging speed. Functional OCT enables label-free monitoring of hemodynamic and metabolic changes in the brain in vitro and in vivo in animal models.

Due to its non-invasiveness nature, OCT enables longitudinal imaging of developing specimens in vivo without potential damage from surgical operation, tissue fixation and processing, and staining with exogenous contrast agents. In this paper, various OCT applications in brain imaging and developmental biology are reviewed, with a particular focus on imaging heart development. In addition, we report findings on HAMA M520 Optical Mouse effects of a circadian gene Clock and high-fat-diet on heart development in Drosophila melanogaster.

These findings contribute to our understanding of the fundamental mechanisms connecting circadian genes and obesity to HAMA M520 Optical Mouse development and cardiac diseases. Biological systems, Biomedical optical imaging, Brain, Cardiovascular system and Optical tomography I. OCT imaging is analogous to ultrasound B-mode imaging, measuring echo time delay of backscattered light.

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Instead of direct measurement of time delay of reflected photons, OCT uses low coherence interferometry to map out back-scattering properties from different depths of samples. OCT is able to provide in situ and in vivo images of tissue morphology with a resolution approaching HAMA M520 Optical Mouse of conventional histology, but without the need to excise or process specimens.

Currently, OCT has been widely used clinically in ophthalmology [ 4 — 10 ], cardiology [ 11 — 15 ], endoscopy [ 16 — 23 ], dermatology [ 24 — 29 ] and oncology [ 24 — 29 ]. In recent years, there has been a growing need for high-speed, high-resolution optical imaging modalities for neuroimaging and developmental biology. Recent development of high speed and ultrahigh resolution HAMA M520 Optical Mouse technologies [ 30 — 33 ] makes it possible to reveal fast dynamics and cellular features of the brain and developing embryos.

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These benefits, combined with label-free and non-invasive imaging capabilities, OCT becomes an attractive research tool for scientists working in these research fields. OCT has been demonstrated as a promising neuroimaging tool [ 34 — 36 ].

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OCT enables non-invasive visualization of structures and functionality of the brain, which is valuable for fundamental research and medical diagnosis. OCT reveals fine structural details of brain HAMA M520 Optical Mouse with the capability to resolve individual neurons and myelinated fibers [ 34 ].

Both structural and functional information provided by OCT has been utilized to study brain diseases, such as brain tumors [ 35 ] HAMA M520 Optical Mouse stroke [ 36 ]. In developmental biology, OCT has been used to characterize morphological and functional development of organs, such as eyes [ 39 ], brain [ 40 ], limbs [ 41 ], reproductive organs [ 42 ] and the heart [ 114043 — 45 ]. The embryonic heart especially, undergoes significant morphological and functional changes during development.


Traditionally, structural changes of the developing heart were evaluated based on histological slides using standard light microscope. OCT is able to provide micron-scale resolution images of cardiac morphology and functionality in vivo without the need for heart dissection and processing. Moreover, OCT imaging is non-invasive, enabling HAMA M520 Optical Mouse studies of the developing heart.

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To date, OCT has been used extensively to study heart development in various animal models, including Xenopus [ 11 ], zebrafish [ 40 ], chicken and quail [ 43 ], mouse [ 44 ] and Drosophila [ 45 ]. In this paper, we HAMA M520 Optical Mouse a comprehensive review of OCT applications for brain imaging and developmental biology. We had previously shown that a circadian clock gene, Cry, plays an essential role in heart morphogenesis and function [ 45 ].

We observed that changes in the expression of dClock resulted in cardiac dysfunction at various developmental stages of the fly. Moreover, obesity is associated with many diseases, including cardiovascular diseases [ 4647 ].


Previous studies showed that high-fat-diet HFD induces metabolic and transcriptional response in Drosophila [ 48 ].

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